I have a function (weisurv) that has 2 parameters - sc and shp. It is a function through time (t). Time is a sequence, i.e. t<-seq(1:100).

```
weisurv<-function(t,sc,shp){
surv<-exp(-(t/sc)^shp)
return(surv)
}
```

I have a data frame (df) that contains a list of sc and shp values (like 300+ of them). For example, I have:

```
M shp sc p C i
1 1 1.138131 10.592154 0.1 1 1
2 1.01 1.143798 10.313217 0.1 1 2
3 1.02 1.160653 10.207863 0.1 1 3
4 1.03 1.185886 9.861997 0.1 1 4
...
```

I want to apply each set (ROW) of sc and shp parameters to my function. So the function would look like weisurv(t,sc[[i]],shp[i]]) for each row[i]. I do not understand how to use apply or adply to do this though I'm sure one of these or a combo of both are what is needed. In the end, I am looking for a data frame that gives a value of weisurv for each time given a set of sc and shp (held constant through time). So if I had 10 sets of sc and shp parameters, I would end up with 10 time series of weisurv. Thanks....

Answer:

Using plyr:

As a matrix (time in cols, rows corresponding to rows of df):

```
aaply(df, 1, function(x) weisurv(t, x$sc, x$shp), .expand = FALSE)
```

As a list:

```
alply(df, 1, function(x) weisurv(t, x$sc, x$shp))
```

As a data frame (structure as per matrix above):

```
adply(df, 1, function(x) setNames(weisurv(t, x$sc, x$shp), t))
```

As a long data frame (one row per t/sc/shp combination); note uses mutate and the pipe operator from `dplyr`

):

```
newDf <- data.frame(t = rep(t, nrow(df)), sc = df$sc, shp = df$shp) %>%
mutate(surv = weisurv(t, sc, shp))
```

You can also create a wide data.frame and then use `reshape2::melt`

to reformat as long:

```
wideDf <- adply(df, 1, function(x) setNames(weisurv(t, x$sc, x$shp), t))
newDf <- melt(wideDf, id.vars = colnames(df), variable.name = "t", value.name = "surv")
newDf$t <- as.numeric(as.character(newDf$t))
```

Pretty plot of last newDf (using ggplot2):

```
ggplot(newDf, aes(x = t, y = surv, col = sprintf("sc = %0.3f, shp = %0.3f", sc, shp))) +
geom_line() +
scale_color_discrete(name = "Parameters")
```

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